Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke

Cigarette smoke (CS) is a main risk factor for chronic obstructive pulmonary disease (COPD). Oxidative stress induced by CS causes DNA and lung damage. Oxidant/antioxidant imbalance occurs in the distal air spaces of smokers and in patients with COPD. We studied the effect of oxidative stress genera...

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Detalhes bibliográficos
Main Authors: Messier, E M, Bahmed, K, Tuder, R M, Chu, H W, Bowler, R P, Kosmider, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668634/
https://ncbi.nlm.nih.gov/pubmed/23559007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.96
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