Zebularine regulates early stages of mESC differentiation: effect on cardiac commitment

Lineage commitment during embryonic stem cell (ESC) differentiation is controlled not only by a gamut of transcription factors but also by epigenetic events, mainly histone deacetylation and promoter DNA methylation. The DNA demethylation agent 5′-aza-2′-deoxycytidine (AzadC) has been widely describ...

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Detalhes bibliográficos
Main Authors: Horrillo, A, Pezzolla, D, Fraga, M F, Aguilera, Y, Salguero-Aranda, C, Tejedo, J R, Martin, F, Bedoya, F J, Soria, B, Hmadcha, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668624/
https://ncbi.nlm.nih.gov/pubmed/23559004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.88
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