Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor Through Virtual Screening

The androgen receptor (AR) is the best studied drug target for the treatment of prostate cancer. While there are a number of drugs that target the AR, they all work through the same mechanism of action and are prone to the development of drug resistance. There is a large unmet need for novel AR inhi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lack, Nathan A., Axerio-Cilies, Peter, Tavassoli, Peyman, Han, Frank Q., Chan, Ka Hong, Feau, Clementine, LeBlanc, Eric, Guns, Emma Tomlinson, Guy, R. Kiplin, Rennie, Paul S., Cherkasov, Artem
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668559/
https://ncbi.nlm.nih.gov/pubmed/22047606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201098n
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