Phenylalanine 664 of dipeptidyl peptidase (DPP) 7 and Phenylalanine 671 of DPP11 mediate preference for P2-position hydrophobic residues of a substrate()

Dipeptidyl peptidases (DPPs) are crucial for the energy metabolism in Porphyromonas gingivalis, a Gram-negative proteolytic and asaccharolytic anaerobic rod causing chronic periodontitis. Three DPPs, DPPIV specific for Pro, DPP7 for hydrophobic residues and DPP11 for Asp/Glu at the P1 position, are...

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Autores principales: Rouf, Shakh M.A., Ohara-Nemoto, Yuko, Ono, Toshio, Shimoyama, Yu, Kimura, Shigenobu, Nemoto, Takayuki K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668534/
https://ncbi.nlm.nih.gov/pubmed/23772391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.03.004
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