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A water-soluble selenoxide reagent as a useful probe for the reactivity and folding of polythiol peptides()

A water-soluble selenoxide (DHS(ox)) having a five-membered ring structure enables rapid and selective conversion of cysteinyl SH groups in a polypeptide chain into SS bonds in a wide pH and temperature range. It was previously demonstrated that the second-order rate constants for the SS formation w...

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Main Authors: Arai, Kenta, Noguchi, Masato, Singh, Beena G., Priyadarsini, K. Indira, Fujio, Katsuhiko, Kubo, Yurika, Takayama, Kyoko, Ando, Setsuko, Iwaoka, Michio
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668528/
https://ncbi.nlm.nih.gov/pubmed/23772375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2012.12.004
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