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Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation

Erythropoiesis is dependent on the lineage-specific transcription factors Gata1, Tal1, and Klf1. Several erythroid genes have been shown to require all 3 factors for their expression, suggesting that they function synergistically; however, there is little direct evidence for widespread cooperation....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, LiQi, Freudenberg, Johannes, Cui, Kairong, Dale, Ryan, Song, Sang-Hyun, Dean, Ann, Zhao, Keji, Jothi, Raja, Love, Paul E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668490/
https://ncbi.nlm.nih.gov/pubmed/23610375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-479451
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