Control of carbohydrate processing: the lec1A CHO mutation results in partial loss of N-acetylglucosaminyltransferase I activity.

Míreanna Comhchosúla

• Control of carbohydrate processing: increased beta-1,6 branching in N-linked carbohydrates of Lec9 CHO mutants appears to arise from a defect in oligosaccharide-dolichol biosynthesis.
  le: Rosenwald, A G, et al.
  Foilsithe: (1989)
• Transfection of a human gene that corrects the Lec1 glycosylation defect: evidence for transfer of the structural gene for N-acetylglucosaminyltransferase I.
  le: Kumar, R, et al.
  Foilsithe: (1989)
• Decreased tumorigenicity correlates with expression of altered cell surface carbohydrates in Lec9 CHO cells.
  le: Ripka, J, et al.
  Foilsithe: (1986)
• Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation.
  le: Kumar, R, et al.
  Foilsithe: (1990)
• Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.
  le: Ioffe, E, et al.
  Foilsithe: (1994)