KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers

BACKGROUND: Mutations in the Kirsten Ras (KRAS) oncogene are common in colorectal cancer (CRC). The role of KRAS-mutation status as a prognostic factor, however, is unclear. We evaluated the relationship between KRAS-mutation status and CRC survival, considering heterogeneity in this association by...

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Detalhes bibliográficos
Main Authors: Phipps, A I, Buchanan, D D, Makar, K W, Win, A K, Baron, J A, Lindor, N M, Potter, J D, Newcomb, P A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668469/
https://ncbi.nlm.nih.gov/pubmed/23511557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.118
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