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Two Mutations associated with Macrolide Resistance in Treponema pallidum: Increasing Prevalence and Correlation with Molecular Strain Type in Seattle, Washington

BACKGROUND: Although azithromycin promised to be a safe and effective single dose oral treatment for early syphilis, azithromycin treatment failure has been documented and is associated with mutations in the 23S rDNA of corresponding Treponema pallidum strains. The prevalence of strains harboring th...

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Detalhes bibliográficos
Main Authors: Grimes, Matthew, Sahi, Sharon K., Godornes, B. Charmie, Tantalo, Lauren C., Roberts, Neal, Bostick, David, Marra, Christina M., Lukehart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668457/
https://ncbi.nlm.nih.gov/pubmed/23191949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/OLQ.0b013e31826ae7a8
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