CG methylated microarrays identify a novel methylated sequence bound by the CEBPB|ATF4 heterodimer that is active in vivo

To evaluate the effect of CG methylation on DNA binding of sequence-specific B-ZIP transcription factors (TFs) in a high-throughput manner, we enzymatically methylated the cytosine in the CG dinucleotide on protein binding microarrays. Two Agilent DNA array designs were used. One contained 40,000 fe...

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Main Authors: Mann, Ishminder K., Chatterjee, Raghunath, Zhao, Jianfei, He, Ximiao, Weirauch, Matthew T., Hughes, Timothy R., Vinson, Charles
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668366/
https://ncbi.nlm.nih.gov/pubmed/23590861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.146654.112
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