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Roles for transcript leaders in translation and mRNA decay revealed by transcript leader sequencing
Transcript leaders (TLs) can have profound effects on mRNA translation and stability. To map TL boundaries genome-wide, we developed TL-sequencing (TL-seq), a technique combining enzymatic capture of m(7)G-capped mRNA 5′ ends with high-throughput sequencing. TL-seq identified mRNA start sites for th...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668365/ https://ncbi.nlm.nih.gov/pubmed/23580730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.150342.112 |
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