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Structure-based whole-genome realignment reveals many novel noncoding RNAs

Recent genome-wide computational screens that search for conservation of RNA secondary structure in whole-genome alignments (WGAs) have predicted thousands of structural noncoding RNAs (ncRNAs). The sensitivity of such approaches, however, is limited, due to their reliance on sequence-based whole-ge...

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Autori principali: Will, Sebastian, Yu, Michael, Berger, Bonnie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668356/
https://ncbi.nlm.nih.gov/pubmed/23296921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.137091.111
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