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The role of microRNAs in the pathogenesis of MMPi-induced skin fibrodysplasia

BACKGROUND: Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes involved in extracellular matrix (ECM) homeostasis. MMPs have been an attractive pharmacological target for a number of indications. However, development has been hampered by the propensity of compounds targeting these...

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Detalhes bibliográficos
Main Authors: Tonge, Daniel P, Tugwood, Jonathan D, Kelsall, Janet, Gant, Timothy W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668254/
https://ncbi.nlm.nih.gov/pubmed/23688202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-338
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