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Effect of Normalization on Statistical and Biological Interpretation of Gene Expression Profiles
An under-appreciated aspect of the genetic analysis of gene expression is the impact of post-probe level normalization on biological inference. Here we contrast nine different methods for normalization of an Illumina bead-array gene expression profiling dataset consisting of peripheral blood samples...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668151/ https://ncbi.nlm.nih.gov/pubmed/23755061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00160 |
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