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Independent immunoglobulin class-switch events occurring in a single myeloma cell line.

Five gamma 2a-producing cell lines, all derived from the gamma 2b-producing mouse myeloma MPC11, were analyzed for changes in gene structure. Also examined was a cell line (ICR9.7.1) that acts as an intermediate to some of these class switches. All six of the MPC11 variants have undergone DNA rearra...

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Autors principals: Eckhardt, L A, Birshtein, B K
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC366791/
https://ncbi.nlm.nih.gov/pubmed/3921826
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