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Prognostic impact of Fas-associated death domain, a key component in death receptor signaling, is dependent on the presence of lymph node metastasis in head and neck squamous cell carcinoma

FAS-associated death domain (FADD) is a key adaptor protein that bridges a death receptor (e.g., death receptor 5; DR5) to caspase-8 to form the death-inducing signaling complex during apoptosis. The expression and prognostic impact of FADD in head and neck squamous cell carcinoma (HNSCC) have not b...

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Bibliografiske detaljer
Main Authors: Fan, Songqing, Müller, Susan, Chen, Zhuo Georgia, Pan, Lin, Tighiouart, Mourad, Shin, Dong M., Khuri, Fadlo R., Sun, Shi-Yong
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667877/
https://ncbi.nlm.nih.gov/pubmed/23358467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23636
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