16 kDa Heat Shock Protein from Heat-Inactivated Mycobacterium tuberculosis Is a Homodimer – Suitability for Diagnostic Applications with Specific Llama VHH Monoclonals

BACKGROUND: The 16 kDa heat shock protein (HSP) is an immuno-dominant antigen, used in diagnosis of infectious Mycobacterium tuberculosis (M.tb.) causing tuberculosis (TB). Its use in serum-based diagnostics is limited, but for the direct identification of M.tb. bacteria in sputum or cultures it may...

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Main Authors: Srivastava, Saurabh K., Ruigrok, Vincent J. B., Thompson, Natalie J., Trilling, Anke K., Heck, Albert J. R., van Rijn, Cees, Beekwilder, Jules, Jongsma, Maarten A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667823/
https://ncbi.nlm.nih.gov/pubmed/23737964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064040
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