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Active Suppression Induced by Repetitive Self-Epitopes Protects against EAE Development
BACKGROUND: Autoimmune diseases result from a breakdown in self-tolerance to autoantigens. Self-tolerance is induced and sustained by central and peripheral mechanisms intended to deviate harmful immune responses and to maintain homeostasis, where regulatory T cells play a crucial role. The use of s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667816/ https://ncbi.nlm.nih.gov/pubmed/23738007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064888 |
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