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Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides.

The classical human interferon-alpha (HuIFN-alpha) gene family is estimated to consist of 15 or more nonallelic members which encode proteins sharing greater than 77% amino acid sequence homology. Low-stringency hybridization with a HuIFN-alpha cDNA probe permitted the isolation of two distinct clas...

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Publicat a:Mol Cell Biol
Autors principals: Capon, D J, Shepard, H M, Goeddel, D V
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2985969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.4.768-779.1985
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