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Interaction of Hb Adana (HBA2: c.179G>A) with Deletional and Nondeletional α (+)-Thalassemia Mutations: Diverse Hematological and Clinical Features

We describe 27 cases of mild-to-severe α-thalassemia (α-thal) syndrome caused by interaction of Hb Adana [α59(E8)Gly→Asp, GGC>GAC (α2)] with deletional and nondeletional α(+)-thal mutations in Indonesian patients. Hematological profiles and clinical manifestations of all patients were assessed by...

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Autori principali: Nainggolan, Ita M., Harahap, Alida, Ambarwati, Debby D., Liliani, Rosalina V., Megawati, Dewi, Swastika, Maria, Setianingsih, Iswari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Informa Healthcare 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667679/
https://ncbi.nlm.nih.gov/pubmed/23614625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03630269.2013.775149
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