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Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells (hESCs) and and Induced Pluripotent Stem Cells (iPSCs)

We present a method for deriving natural killer (NK) cells from undifferentiated hESCs and iPSCs using a feeder-free approach. This method gives rise to high levels of NK cells after 4 weeks culture and can undergo further 2-log expansion with artificial antigen presenting cells. hESC- and iPSC-deri...

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Detalhes bibliográficos
Main Authors: Bock, Allison M., Knorr, David, Kaufman, Dan S.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667548/
https://ncbi.nlm.nih.gov/pubmed/23644738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50337
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