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Genetic and epigenetic inactivation of LPL gene in human prostate cancer

Lipoprotein lipase (LPL) is in chromosome 8p22, site of one of the most common somatic deletions in prostate tumors. Additionally, a CpG island (CGI) was identified in the LPL promoter region. To test the hypothesis that LPL is a tumor suppressor gene, which is inactivated by somatic deletion and hy...

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Detalhes bibliográficos
Main Authors: Kim, Jin Woo, Cheng, Yu, Liu, Wennuan, Li, Tao, Yegnasubramanian, Srinivasan, Zheng, Siqun L., Xu, Jianfeng, Isaacs, William B., Chang, Bao-Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667349/
https://ncbi.nlm.nih.gov/pubmed/19004026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23972
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