Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells

BACKGROUND: A sophisticated level of coordinated gene expression is necessary for skeletal muscle fibers to obtain their unique functional identities. We have previously shown that the transcription factor Sox6 plays an essential role in coordinating muscle fiber type differentiation by acting as a...

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Detaylı Bibliyografya
Asıl Yazarlar: An, Chung-Il, Ganio, Edward, Hagiwara, Nobuko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666947/
https://ncbi.nlm.nih.gov/pubmed/23663701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-11
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