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Structural basis of the relaxed state of a Ca(2+)-regulated myosin filament and its evolutionary implications

Myosin filaments of muscle are regulated either by phosphorylation of their regulatory light chains or Ca(2+) binding to the essential light chains, contributing to on–off switching or modulation of contraction. Phosphorylation-regulated filaments in the relaxed state are characterized by an asymmet...

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Bibliografiske detaljer
Main Authors: Woodhead, John L., Zhao, Fa-Qing, Craig, Roger
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666738/
https://ncbi.nlm.nih.gov/pubmed/23650385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218462110
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