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Female mice lack adult germ-line stem cells but sustain oogenesis using stable primordial follicles

Whether or not mammalian females generate new oocytes during adulthood from germ-line stem cells to sustain the ovarian follicle pool has recently generated controversy. We used a sensitive lineage-labeling system to determine whether stem cells are needed in female adult mice to compensate for foll...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lei, Lei, Spradling, Allan C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666718/
https://ncbi.nlm.nih.gov/pubmed/23630252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306189110
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