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Activated microglia enhance neurogenesis via trypsinogen secretion

White matter neurons in multiple sclerosis brains are destroyed during demyelination and then replaced in some chronic multiple sclerosis lesions that exhibit a morphologically distinct population of activated microglia [Chang A, et al. (2008) Brain 131(Pt 9):2366–2375]. Here we investigated whether...

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Détails bibliographiques
Auteurs principaux: Nikolakopoulou, Angeliki M., Dutta, Ranjan, Chen, Zhihong, Miller, Robert H., Trapp, Bruce D.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666689/
https://ncbi.nlm.nih.gov/pubmed/23650361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218856110
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