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Phosphorylation-dependent conformational changes and domain rearrangements in Staphylococcus aureus VraR activation

Staphylococcus aureus VraR, a vancomycin-resistance-associated response regulator, activates a cell-wall–stress stimulon in response to antibiotics that inhibit cell wall formation. X-ray crystal structures of VraR in both unphosphorylated and beryllofluoride-activated states have been determined, r...

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Détails bibliographiques
Auteurs principaux: Leonard, Paul G., Golemi-Kotra, Dasantila, Stock, Ann M.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666669/
https://ncbi.nlm.nih.gov/pubmed/23650349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302819110
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