Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site

The Mycobacterium tuberculosis genome contains an unusually high number of toxin–antitoxin modules, some of which have been suggested to play a role in the establishment and maintenance of latent tuberculosis. Nine of these toxin–antitoxin loci belong to the mazEF family, encoding the intracellular...

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Detaylı Bibliyografya
Asıl Yazarlar: Schifano, Jason M., Edifor, Regina, Sharp, Jared D., Ouyang, Ming, Konkimalla, Arvind, Husson, Robert N., Woychik, Nancy A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666664/
https://ncbi.nlm.nih.gov/pubmed/23650345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222031110
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