A Safe Bacterial Microsyringe for In Vivo Antigen Delivery and Immunotherapy

The industrial development of active immunotherapy based on live-attenuated bacterial vectors has matured. We developed a microsyringe for antigen delivery based on the type III secretion system (T3SS) of P. aeruginosa. We applied the “killed but metabolically active” (KBMA) attenuation strategy to...

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Detalhes bibliográficos
Main Authors: Le Gouëllec, Audrey, Chauchet, Xavier, Laurin, David, Aspord, Caroline, Verove, Julien, Wang, Yan, Genestet, Charlotte, Trocme, Candice, Ahmadi, Mitra, Martin, Sandrine, Broisat, Alexis, Cretin, François, Ghezzi, Catherine, Polack, Benoit, Plumas, Joël, Toussaint, Bertrand
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666637/
https://ncbi.nlm.nih.gov/pubmed/23531551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.41
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