Functional Mechanotransduction Is Required for Cisplatin-Induced Hair Cell Death in the Zebrafish Lateral Line

Cisplatin, one of the most commonly used anticancer drugs, is known to cause inner ear hair cell damage and hearing loss. Despite much investigation into mechanisms of cisplatin-induced hair cell death, little is known about the mechanism whereby cisplatin is selectively toxic to hair cells. Using h...

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Hlavní autoři: Thomas, Andrew J., Hailey, Dale W., Stawicki, Tamara M., Wu, Patricia, Coffin, Allison B., Rubel, Edwin W, Raible, David W., Simon, Julian A., Ou, Henry C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666553/
https://ncbi.nlm.nih.gov/pubmed/23467357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3940-12.2013
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