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Multi-functional norrin is a ligand for the LGR4 receptor

Mammalian LGR4, 5 and 6 are seven-transmembrane receptors that are important for diverse physiological processes. These receptors are orthologous to DLGR2, a Drosophila receptor activated by the burs/pburs heterodimer important for morphogenesis. Although recent studies indicated that four R-spondin...

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Hlavní autoři: Deng, Cheng, Reddy, Pradeep, Cheng, Yuan, Luo, Ching-Wei, Hsiao, Chih-Lun, Hsueh, Aaron J. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666258/
https://ncbi.nlm.nih.gov/pubmed/23444378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.123471
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