S-Adenosyl-L-Methionine Augmentation in Patients with Stage II Treatment-Resistant Major Depressive Disorder: An Open Label, Fixed Dose, Single-Blind Study

We investigated the efficacy of S-Adenosyl-L-Methionine (SAMe) augmentation in patients with treatment-resistant depressive disorder (TRD). Thirty-three outpatients with major depressive episode who failed to respond to at least 8 weeks of treatment with two adequate and stable doses of antidepressa...

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Detalhes bibliográficos
Main Authors: De Berardis, Domenico, Marini, Stefano, Serroni, Nicola, Rapini, Gabriella, Iasevoli, Felice, Valchera, Alessandro, Signorelli, Maria, Aguglia, Eugenio, Perna, Giampaolo, Salone, Anatolia, Di Iorio, Giuseppe, Martinotti, Giovanni, Di Giannantonio, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666233/
https://ncbi.nlm.nih.gov/pubmed/23766680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/204649
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