IRF4 Transcription Factor-Dependent CD11b(+) Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

Mouse and human dendritic cells (DCs) are composed of functionally specialized subsets, but precise interspecies correlation is currently incomplete. Here, we showed that murine lung and gut lamina propria CD11b(+) DC populations were comprised of two subsets: FLT3- and IRF4-dependent CD24(+)CD64(−)...

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Main Authors: Schlitzer, Andreas, McGovern, Naomi, Teo, Pearline, Zelante, Teresa, Atarashi, Koji, Low, Donovan, Ho, Adrian W.S., See, Peter, Shin, Amanda, Wasan, Pavandip Singh, Hoeffel, Guillaume, Malleret, Benoit, Heiseke, Alexander, Chew, Samantha, Jardine, Laura, Purvis, Harriet A., Hilkens, Catharien M.U., Tam, John, Poidinger, Michael, Stanley, E. Richard, Krug, Anne B., Renia, Laurent, Sivasankar, Baalasubramanian, Ng, Lai Guan, Collin, Matthew, Ricciardi-Castagnoli, Paola, Honda, Kenya, Haniffa, Muzlifah, Ginhoux, Florent
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666057/
https://ncbi.nlm.nih.gov/pubmed/23706669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.04.011
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