Design of an Interpolyelectrolyte Gastroretentive Matrix for the Site-Specific Zero-Order Delivery of Levodopa in Parkinson’s Disease

This study focused on developing a gastroretentive drug delivery system employing a triple-mechanism interpolyelectrolyte complex (IPEC) matrix comprising high density, swelling, and bioadhesiveness for the enhanced site-specific zero-order delivery of levodopa in Parkinson’s disease. An IPEC was sy...

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Detalhes bibliográficos
Main Authors: Ngwuluka, Ndidi C., Choonara, Yahya E., Modi, Girish, du Toit, Lisa C., Kumar, Pradeep, Ndesendo, Valence M. K., Pillay, Viness
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666024/
https://ncbi.nlm.nih.gov/pubmed/23494468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9945-1
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