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Dual Host-Virus Arms Races Shape an Essential Housekeeping Protein

Transferrin Receptor (TfR1) is the cell-surface receptor that regulates iron uptake into cells, a process that is fundamental to life. However, TfR1 also facilitates the cellular entry of multiple mammalian viruses. We use evolutionary and functional analyses of TfR1 in the rodent clade, where two f...

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Hlavní autoři: Demogines, Ann, Abraham, Jonathan, Choe, Hyeryun, Farzan, Michael, Sawyer, Sara L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665890/
https://ncbi.nlm.nih.gov/pubmed/23723737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001571
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