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Global Gene Expression Profiling in PAI-1 Knockout Murine Heart and Kidney: Molecular Basis of Cardiac-Selective Fibrosis

Fibrosis is defined as an abnormal matrix remodeling due to excessive synthesis and accumulation of extracellular matrix proteins in tissues during wound healing or in response to chemical, mechanical and immunological stresses. At present, there is no effective therapy for organ fibrosis. Previous...

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Detalhes bibliográficos
Main Authors: Ghosh, Asish K., Murphy, Sheila B., Kishore, Raj, Vaughan, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665822/
https://ncbi.nlm.nih.gov/pubmed/23724005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063825
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