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GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior

Impaired GABA–mediated neurotransmission has been implicated in many neurologic diseases including epilepsy, intellectual disability, and psychiatric disorders. Here we report that inhibitory neuron transplantation into the hippocampus of adult mice with confirmed epilepsy at the time of grafting dr...

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Detalhes bibliográficos
Main Authors: Hunt, Robert F., Girskis, Kelly M., Rubenstein, John L., Alvarez–Buylla, Arturo, Baraban, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665733/
https://ncbi.nlm.nih.gov/pubmed/23644485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3392
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