Antioxidant-mediated up-regulation of OGG1 via NRF2 induction is associated with inhibition of oxidative DNA damage in estrogen-induced breast cancer

BACKGROUND: Estrogen metabolism-mediated oxidative stress is suggested to play an important role in estrogen-induced breast carcinogenesis. We have earlier demonstrated that antioxidants, vitamin C (Vit C) and butylated hydroxyanisole (BHA) inhibit 17β-estradiol (E2)-mediated oxidative stress and ox...

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Main Authors: Singh, Bhupendra, Chatterjee, Anwesha, Ronghe, Amruta M, Bhat, Nimee K, Bhat, Hari K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665669/
https://ncbi.nlm.nih.gov/pubmed/23697596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-253
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