A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model

BACKGROUND: Acute graft-versus-host disease (aGVHD) poses a major limitation for broader therapeutic application of allogeneic hematopoietic cell transplantation (allo-HCT). Early diagnosis of aGVHD remains difficult and is based on clinical symptoms and histopathological evaluation of tissue biopsi...

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Main Authors: Bäuerlein, Carina A, Riedel, Simone S, Baker, Jeanette, Brede, Christian, Garrote, Ana-Laura Jordán, Chopra, Martin, Ritz, Miriam, Beilhack, Georg F, Schulz, Stephan, Zeiser, Robert, Schlegel, Paul G, Einsele, Hermann, Negrin, Robert S, Beilhack, Andreas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665617/
https://ncbi.nlm.nih.gov/pubmed/23692886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-11-134
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