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Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder

BACKGROUND: We have recently identified the nuclear hormone receptor RORA (retinoic acid-related orphan receptor-alpha) as a novel candidate gene for autism spectrum disorder (ASD). Our independent cohort studies have consistently demonstrated the reduction of RORA transcript and/or protein levels i...

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Autors principals: Sarachana, Tewarit, Hu, Valerie W
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665583/
https://ncbi.nlm.nih.gov/pubmed/23697635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-4-14
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