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Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma

The epidermal growth-factor receptor (EGFR) is overexpressed in the majority of epithelial ovarian cancers and promotes cell proliferation, migration and invasion, and angiogenesis, as well as resistance to apoptosis. This makes EGFR an attractive therapeutic target in this disease. A number of stra...

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Detalhes bibliográficos
Autor principal: Hirte, Hal W
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665572/
https://ncbi.nlm.nih.gov/pubmed/23723710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S30373
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