GWIS - model-free, fast and exhaustive search for epistatic interactions in case-control GWAS

BACKGROUND: It has been hypothesized that multivariate analysis and systematic detection of epistatic interactions between explanatory genotyping variables may help resolve the problem of "missing heritability" currently observed in genome-wide association studies (GWAS). However, even the...

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Hlavní autoři: Goudey, Benjamin, Rawlinson, David, Wang, Qiao, Shi, Fan, Ferra, Herman, Campbell, Richard M, Stern, Linda, Inouye, Michael T, Ong, Cheng Soon, Kowalczyk, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665501/
https://ncbi.nlm.nih.gov/pubmed/23819779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-S3-S10
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