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Validation of suitable endogenous control genes for quantitative PCR analysis of microRNA gene expression in a rat model of endometrial cancer

BACKGROUND: MicroRNAs are small RNA molecules that negatively regulate gene expression by translational inhibition or mRNA cleavage. The discovery that abnormal expression of particular miRNAs contributes to human disease, including cancer, has spurred growing interest in analysing expression profil...

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Bibliographic Details
Main Authors: Jurcevic, Sanja, Olsson, Björn, Klinga-Levan, Karin
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665477/
https://ncbi.nlm.nih.gov/pubmed/23680393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-45
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