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Osteogenic Differentiation of Adipose-Derived Stem Cells Is Hypoxia-Inducible Factor-1 Independent
Tissue engineering is a promising approach to repair critical-size defects in bone. Damage to vasculature at the defect site can create a lower O(2) environment compared with healthy bone. Local O(2) levels influence stem cell behavior, as O(2) is not only a nutrient, but also a signaling molecule....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665297/ https://ncbi.nlm.nih.gov/pubmed/23394201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2012.0378 |
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