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Decursin Isolated from Angelica gigas Nakai Rescues PC12 Cells from Amyloid β-Protein-Induced Neurotoxicity through Nrf2-Mediated Upregulation of Heme Oxygenase-1: Potential Roles of MAPK

Decursin (D), purified from Angelica gigas Nakai, has been proven to exert neuroprotective property. Previous study revealed that D reduced Aβ (25‒35)-induced cytotoxicity in PC12 cells. Our study explored the underlying mechanisms by which D mediates its therapeutic effects in vitro. Pretreatment o...

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Autores principales: Li, Li, Du, Ji-kun, Zou, Li-yi, Wu, Tie, Lee, Yong-woo, Kim, Yong-ho
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665219/
https://ncbi.nlm.nih.gov/pubmed/23762139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/467245
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