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LNCaP Prostate Cancer Cells with Autocrine Interleukin-6 Expression Are Resistant to IL-6-induced Neuroendocrine Differentiation due to Increased Expression of Suppressors of Cytokine Signaling
BACKGROUND: Neuroendocrine differentiation (NED) is one of the mechanisms underlying development of castration-resistant prostate cancer. In this study, we investigated IL-6-induced NED in two LNCaP sublines. METHODS: LNCaP-S17, an LNCaP subline that secretes IL-6, and LNCaP-C3, a control subline th...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665156/ https://ncbi.nlm.nih.gov/pubmed/22213096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22479 |
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