LNCaP Prostate Cancer Cells with Autocrine Interleukin-6 Expression Are Resistant to IL-6-induced Neuroendocrine Differentiation due to Increased Expression of Suppressors of Cytokine Signaling

BACKGROUND: Neuroendocrine differentiation (NED) is one of the mechanisms underlying development of castration-resistant prostate cancer. In this study, we investigated IL-6-induced NED in two LNCaP sublines. METHODS: LNCaP-S17, an LNCaP subline that secretes IL-6, and LNCaP-C3, a control subline th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ge, Dongxia, Gao, Allen C., Zhang, Qiuyang, Liu, Sen, Xue, Yun, You, Zongbing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665156/
https://ncbi.nlm.nih.gov/pubmed/22213096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22479
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia