IL-33 induces innate lymphoid cell–mediated airway inflammation by activating mammalian target of rapamycin

BACKGROUND: The IL-1 family cytokine IL-33 is involved in the induction of airway inflammation in allergic patients and after viral infection. Several cell types, including CD4(+) T(H)2 cells and the recently described type 2 innate lymphoid cells (ILCs), are targets for IL-33, yet the mechanisms by...

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Hlavní autoři: Salmond, Robert J., Mirchandani, Ananda S., Besnard, Anne-Gaelle, Bain, Calum C., Thomson, Neil C., Liew, Foo Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mosby 2012
Témata:
Mechanisms of Allergy and Clinical Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664950/
https://ncbi.nlm.nih.gov/pubmed/22738676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.05.018
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