Cryo–electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering

Synaptic vesicles are embedded in a complex filamentous network at the presynaptic terminal. Before fusion, vesicles are linked to the active zone (AZ) by short filaments (tethers). The identity of the molecules that form and regulate tethers remains unknown, but Rab3-interacting molecule (RIM) is a...

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Autori principali: Fernández-Busnadiego, Rubén, Asano, Shoh, Oprisoreanu, Ana-Maria, Sakata, Eri, Doengi, Michael, Kochovski, Zdravko, Zürner, Magdalena, Stein, Valentin, Schoch, Susanne, Baumeister, Wolfgang, Lučić, Vladan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2013
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664715/
https://ncbi.nlm.nih.gov/pubmed/23712261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201206063
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