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Detection of Nucleic Acid Targets Using Ramified Rolling Circle DNA Amplification: A Single Nucleotide Polymorphism Assay Model

BACKGROUND: Isothermal amplification methods provide alternatives to PCR that may be preferable for some nucleic acid target detection tasks. Among current isothermal target detection methods, ramified rolling circle amplification (RAM) of single-stranded DNA circles that are formed by ligation of l...

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Detalles Bibliográficos
Main Authors: Smith, James H., Beals, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664557/
https://ncbi.nlm.nih.gov/pubmed/23724122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065053
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