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The Essential Role of stacking adenines in a Two-Base-Pair RNA Kissing Complex
In minimal RNA kissing complexes formed between hairpins with cognate GACG tetraloops, the two tertiary GC pairs are likely stabilized by the stacking of 5’-unpaired adenines at each end of the short helix. To test this hypothesis, we mutated the flanking adenines to various nucleosides and examined...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664431/ https://ncbi.nlm.nih.gov/pubmed/23517345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja310820h |
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